TB‑500

1. Product Overview

TB‑500 is a synthetic bioactive peptide fragment derived from Thymosin Beta‑4 (Tβ4), retaining the core actin‑binding functional motif of full‑length Tβ4 with superior solubility and stability. Our TB‑500 is manufactured via standardized solid‑phase peptide synthesis and vacuum freeze‑drying to form uniform white lyophilized powder.

It serves as a key actin‑sequestering agent inside cells, regulating cytoskeleton dynamics, stimulating endothelial cell migration and new blood vessel formation (angiogenesis), while modulating inflammatory cytokines to reduce tissue swelling and scarring. It is the mainstream research reagent for regenerative medicine, sports injury recovery and skin wound repair laboratory projects. Each batch undergoes strict HPLC purity detection and mass spectrometry structural identification; complete Certificate of Analysis, HPLC chromatograms and MS spectra are provided for all orders to guarantee stable, repeatable experimental data.

Basic chemical information:

CAS Number: 77591‑33‑4
Molecular Weight: 4963.5 g/mol

2. Available Specifications

SKU Options:

BT5: 5mg per vial, 10 vials per kit
BT10: 10mg per vial, 10 vials per kit

Custom bulk synthesis and customized single‑vial dosage can be arranged upon customer demand for large‑scale cell culture and animal injury model trials.

3. Core Preclinical Research Applications

Tendon, Ligament & Skeletal Muscle Regeneration Research

Promotes tenocyte, myocyte proliferation and collagen matrix deposition; extensively applied in rodent models of muscle contusion, tendon tear, joint ligament damage and sports soft tissue recovery.
Skin Wound Healing & Scar Inhibition Studies

Accelerates epidermal cell migration, boosts angiogenesis at wound sites and reduces fibrotic scar tissue formation; suitable for burn injury, surgical incision and chronic ulcer exploratory experiments.
Anti‑Inflammation & Tissue Protection Research

Downregulates pro‑inflammatory factors TNF‑α, IL‑1β and relieves oxidative stress damage, ideal for joint inflammatory lesions and organ ischemia‑reperfusion injury research.
Cardiovascular Angiogenesis Research

Activates VEGF signaling pathway to induce microvascular regeneration, used for myocardial injury, peripheral circulation disorder and ischemic tissue repair mechanism studies.
Composite Regenerative Peptide Stack Research

Commonly compounded with BPC‑157, GHK‑CU and KPV to develop multi‑target repair formulas, including BB10/BB20/BB30, CG06, BBG70 and KLOW80 compound peptide kits.

4. Strict Quality Control Standards

HPLC purity ≥98%
Mass spectrometry (MS) full structural identity verification
Endotoxin level controlled below 0.1 EU/mg
Independent batch COA, HPLC chromatogram and MS spectrum attached
Comprehensive inspection of residual solvents, heavy metals, oxidation impurities and moisture

5. Storage & Shipping Guidance

Lyophilized powder storage: Seal tightly, store at -20°C, avoid light, high temperature and humid environment; stable for over 24 months under proper sealed preservation.
After reconstitution: Store at 2–8°C, separate into small aliquots and avoid repeated freeze‑thaw cycles to prevent peptide activity attenuation.
Global delivery: Low‑temperature insulated cold‑chain packaging protects peptide biological activity during cross‑border transportation.
Technical service: Our professional R&D team provides reconstitution protocols, storage specifications and experimental scheme consultation within 24 working hours.

6. Important Disclaimer

This lyophilized TB‑500 peptide powder is for laboratory research use only. It is not approved for human injection, oral administration, clinical treatment or veterinary medication. All test data and product introductions are for academic laboratory exploration purposes only.